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Synthesis of a 1,8-naphthyridin-5-one derivative via an intramolecular 1,3-dipolar cycloaddition reaction

✍ Scribed by Mark W. Read; Partha S. Ray

Book ID
112131372
Publisher
Journal of Heterocyclic Chemistry
Year
1995
Tongue
English
Weight
221 KB
Volume
32
Category
Article
ISSN
0022-152X

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Diastereoselective synthesis of nicotine
Diastereoselective synthesis of nicotine derivatives via 1,3-dipolar cycloaddition reactions
✍ Mehdi Ghandi; Abuzar Taheri; Alireza Abbasi πŸ“‚ Article πŸ“… 2010 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 339 KB

## Abstract magnified image A simple diastereoselective route to nicotine derivatives is presented. The one‐pot three component 1,3‐dipolar cycloaddition reaction of the KnΓΆevenagel adducts of a number of aromatic aldehydes and malononitrile with an azomethine ylide derived __in situ__ from pyridin