An Efficient Synthesis of New Dispiropyrrolidine Derivatives via Three-Component 1,3-Dipolar Cycloaddition Reaction
✍ Scribed by Hu, Yu; Shi, Da-Qing
- Book ID
- 120614636
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2013
- Tongue
- English
- Weight
- 279 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-152X
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## Abstract A series of dispiropyrrolidine derivatives were synthesized via the three‐component 1,3‐dipolar cycloaddition reaction of isatin, sarcosine and 5‐arylidene‐1,3‐thiazolidine‐2,4‐dione or 5‐arylidene‐4‐thioxo‐1,3‐thiazolidine‐2‐one in ethanol under ultrasound irradiation. This protocol ha
## Abstract magnified image A simple diastereoselective route to nicotine derivatives is presented. The one‐pot three component 1,3‐dipolar cycloaddition reaction of the Knöevenagel adducts of a number of aromatic aldehydes and malononitrile with an azomethine ylide derived __in situ__ from pyridin