N,N'-Diarylbisnitrile imides 2 add regioselectively to Β’t-(benzothiazol-2-yl)cinnamonitriles 3 and ct-(l-methylbenzimidazol-2-yl)cinnamonitriles 7 to yield exclusively the cycloadducts 5,5'-dicyano-4,4',5,5'-tetrahydro[3,3'-bi-lH-pyrazoles] 4 and 8, respectively. Compounds 4 and 8 undergo aromatizat
Synthesis and Antifungal Activities of New Pyrazole Derivatives via 1,3-dipolar Cycloaddition Reaction
β Scribed by Chuan-Yu Zhang; Xing-Hai Liu; Bao-Lei Wang; Su-Hua Wang; Zheng-Ming Li
- Book ID
- 111368817
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 150 KB
- Volume
- 75
- Category
- Article
- ISSN
- 1747-0277
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## Abstract magnified image A simple diastereoselective route to nicotine derivatives is presented. The oneβpot three component 1,3βdipolar cycloaddition reaction of the KnΓΆevenagel adducts of a number of aromatic aldehydes and malononitrile with an azomethine ylide derived __in situ__ from pyridin
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