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An efficient one-pot synthesis of dispiropyrrolidine derivatives through 1,3-dipolar cycloaddition reactions under ultrasound irradiation

✍ Scribed by Hai Liu; Yi Zou; Yu Hu; Da-Qing Shi

Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
125 KB
Volume
48
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

A series of dispiropyrrolidine derivatives were synthesized via the three‐component 1,3‐dipolar cycloaddition reaction of isatin, sarcosine and 5‐arylidene‐1,3‐thiazolidine‐2,4‐dione or 5‐arylidene‐4‐thioxo‐1,3‐thiazolidine‐2‐one in ethanol under ultrasound irradiation. This protocol has the advantages of mild reaction conditions, higher yields, and shorter reaction time. J. Heterocyclic Chem., (2011).

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