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An efficient one-pot synthesis of polyhydrobenzoacridine-1-one derivatives under microwave irradiation without catalyst

✍ Scribed by Shujiang Tu; Runhong Jia; Bo Jiang; Yan Zhang; Junyong Zhang


Publisher
Journal of Heterocyclic Chemistry
Year
2006
Tongue
English
Weight
333 KB
Volume
43
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

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A series of 3,3‐dimethyl‐9‐substituted‐1,2,3,4,9,10‐hexahydrobenzo[c] acridine‐1‐ones and 3,3‐dimethyl‐9‐substituted‐1,2,3,4,9,10‐hexahydrobenzo[a] acridine‐1‐ones were synthesized by the reaction of an aldehyde, α‐naphthylamine or β‐naphthylamine and dimedone under microwave irradiation with short times and high yields.


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✍ Shujiang Tu; Fang Fang; Tuanjie Li; Songlei Zhu; Xiaojing Zhang 📂 Article 📅 2005 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 53 KB

A series of pyrimidoquinoline derivatives were synthesized through one-pot condensation of 2,6diaminopyrimidin-4-one, aldehyde and cyclic a 1,3-dicarbonyl compound in glycol under microwave irradiation without catalyst. The protocol in the absence of catalyst has the advantage of good yield (87-95%)