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An efficient one-pot synthesis of novel pyrimidoquinoline derivatives under microwave irradiation without catalyst

✍ Scribed by Shujiang Tu; Fang Fang; Tuanjie Li; Songlei Zhu; Xiaojing Zhang


Publisher
Journal of Heterocyclic Chemistry
Year
2005
Tongue
English
Weight
53 KB
Volume
42
Category
Article
ISSN
0022-152X

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✦ Synopsis


A series of pyrimidoquinoline derivatives were synthesized through one-pot condensation of 2,6diaminopyrimidin-4-one, aldehyde and cyclic a 1,3-dicarbonyl compound in glycol under microwave irradiation without catalyst. The protocol in the absence of catalyst has the advantage of good yield (87-95%), short reaction time (4-7 min) and an environmentally friendly technique.


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