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An efficient one-pot synthesis of n-carboxymethylacridine-1,8-dione derivatives under microwave irradiation

✍ Scribed by Shujiang Tu; Qian Wang; Yan Zhang; Jianing Xu; Jinpeng Zhang; Xiaotong Zhu; Feng Shi

Publisher
Journal of Heterocyclic Chemistry
Year
2006
Tongue
English
Weight
286 KB
Volume
43
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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A series of N‐carboxymethylacridine‐1,8‐dione derivatives were synthesized by one‐pot reaction of aldehyde, dimedone and glycine in glycol under microwave irradiation without catalyst with excellent yields (78‐92%) and short reaction time (4‐8min). And the reaction was not only suitable for aromatic monoaldehyde, but also aromatic dialdehyde.

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