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One-pot synthesis of novel N-cyclopropyldecahydroacridine-1,8-dione derivatives under microwave irradiation

✍ Scribed by Shujiang Tu; Xiaojing Zhang; Feng Shi; Tuanjie Li; Qian Wang; Xiaotong Zhu; Jinpeng Zhang; Jianing Xu

Publisher
Journal of Heterocyclic Chemistry
Year
2005
Tongue
English
Weight
104 KB
Volume
42
Category
Article
ISSN
0022-152X

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✦ Synopsis

A series of new N-cyclopropyldecahydroacridine-1,8-dione derivatives were synthesized by one-pot reaction of aromatic aldehyde, dimedone (or 1,3-cyclohexanedione) and cyclopropanamine in solution of glycol and water under microwave irradiation with excellent yields (78-94%) and short reaction time (5-10 min).

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✍ Shujiang Tu; Qian Wang; Yan Zhang; Jianing Xu; Jinpeng Zhang; Xiaotong Zhu; Feng πŸ“‚ Article πŸ“… 2006 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 286 KB πŸ‘ 1 views

## Abstract magnified image A series of __N__‐carboxymethylacridine‐1,8‐dione derivatives were synthesized by one‐pot reaction of aldehyde, dimedone and glycine in glycol under microwave irradiation without catalyst with excellent yields (78‐92%) and short reaction time (4‐8min). And the reaction