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One-Pot synthesis of a novel compound N-hydroxydecahydroacridine under microwave irradiation

โœ Scribed by Shujiang Tu; Fang Fang; Songlei Zhu; Tuanjie Li; Xiaojing Zhang; Qiya Zhuang

Publisher
Journal of Heterocyclic Chemistry
Year
2004
Tongue
English
Weight
173 KB
Volume
41
Category
Article
ISSN
0022-152X

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One-Pot synthesis of a novel compound N-
One-Pot synthesis of a novel compound N-hydroxydecahydroacridine under microwave irradiation
โœ Shujiang Tu; Fang Fang; Songlei Zhu; Tuanjie Li; Xiaojing Zhang; Qiya Zhuang ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 173 KB

## Abstract A novel reaction to synthesis a series new __N__โ€hydroxyldecahydroacridine derivatives by a oneโ€pot condensation of aldehyde, 1,3โ€dicarbonyl compound and NH~2~OH in glycol under microwave irradiation is described. __N__โ€hydroxyldecahydroacridine was obtained in excellent yields (81โ€“95%)

One-pot synthesis of novel N-cyclopropyl
One-pot synthesis of novel N-cyclopropyldecahydroacridine-1,8-dione derivatives under microwave irradiation
โœ Shujiang Tu; Xiaojing Zhang; Feng Shi; Tuanjie Li; Qian Wang; Xiaotong Zhu; Jinp ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 104 KB ๐Ÿ‘ 1 views

A series of new N-cyclopropyldecahydroacridine-1,8-dione derivatives were synthesized by one-pot reaction of aromatic aldehyde, dimedone (or 1,3-cyclohexanedione) and cyclopropanamine in solution of glycol and water under microwave irradiation with excellent yields (78-94%) and short reaction time (