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A total synthesis of the naturally occurring pyrrolo[2,3-d]pyrimidine nucleoside, mycalisine A

โœ Scribed by Eric A. Meade; Steven H. Krawczyk; Leroy B. Townsend*


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
196 KB
Volume
29
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


The first total synthesis of mycalisine A, a pyrrolo[2,3-dlpyrimidine nucleoside, was accomplished by a multi-step synthesis from toyocamycin.


๐Ÿ“œ SIMILAR VOLUMES


Pyrrolopyrimidine nucleosides 19. A tota
โœ Vladimir G Beylin; Andrew M Kawasaki; Chin Shu Cheng; Leroy B Townsend ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 220 KB

A total synthesis of 2-amino-7-(O-D-ribofuranosyl)pyrrolo[2,3-dlpyrimidin-4-one-5-carboxylic acid has been accomplished and confirms the previous structural assignment for the nucleoside antibiotic cadeguomycin.

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โœ Richard L. Tolman; Leroy B. Townsend ๐Ÿ“‚ Article ๐Ÿ“… 1968 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 165 KB

We wish to report the synthesis of a new tricyclic ring system, pyrazolo[3',~'-5,4]pyrrolo[2,3-d]pyrimidine, by a unique ring closure procedure. In the course of our investigation of the chemistry of the pyrrolo[2,3-dJl~rrimidine nueleoside antibiotics, 3 tubercidin, toyocamycin,