[2‐^14^ C]2,5‐dichloropyrimidine is a useful reagent for labeling biologically active compounds for use in hepatocyte transport studies, protein covalent binding, and metabolic profiling. This paper describes a novel five‐step synthesis of [2‐^14^ C]2,5‐dichloropyrimidine from readily available [^14
A novel synthesis of ethanolamine-2-14C
✍ Scribed by E. Koltai; B. Horváth; D. Bánfi
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- French
- Weight
- 248 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
Ethanolamine‐2‐^14^C was prepared by the reduction of benzyloxycarbonyl‐glycine‐1‐^14^C methyl ester. The reduction was carried out with calcium borohydride and the protecting group was removed by hydrogenolysis.
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