## Abstract 4‐|2‐(Dimethylamino)ethyl‐2‐^14^C| phenol (hordenine‐α‐^14^C) has been synthesised in three steps from |^14^C|potassium cyanide and __p__‐benzyloxybenzyl chloride which in turn was obtained in four steps from __p__‐hydroxybenzoic acid.
A convenient synthesis of 2 - [14C] - hordenine
✍ Scribed by George A. Digenis; J. W. Burkett; V. Mihranian
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- French
- Weight
- 165 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
A simple and convenient laboratory procedure is described by which hordenine (III), labelled at the carbon residing on the benzene ring, can be synthesized by decarboxylation of 3‐ [^14^C]‐tyrosine (1) and subsequent reductive methylation of the resulting tyramine (II).
📜 SIMILAR VOLUMES
## Abstract [2,6‐^14^C]‐2‐chloroisonicotinic acid (1) was prepared by kinetically controlled lithiation and carbonation of [2,6‐^14^C]‐2,6‐dichloropyridine, followed by reduction using hydrazine and potassium hydroxide. Copyright © 2001 John Wiley & Sons, Ltd.
## Abstract A convenient synthesis with analytical monitoring of ^14^C‐cotinine is reported. ^14^C‐Nicotine was converted into ^14^C‐dibromocotinine hydrobromide perbromide. Debromination, achieved by using Zn dust/acetic acid, resulted in high yields (71%) of ^14^C‐cotinine.
## Abstract [2‐^14^C]‐Methylglyoxal bis(guanylhydrazone) dihydrochloride, [^14^C]‐mitoguazone, 3, has been prepared in three steps from potassium [1‐^14^C]‐acetate in an overall radiochemical yield of 16%. The key steps in this procedure are the formation of the sodium salt of [__acetone__‐2‐^14^C]