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A convenient synthesis of 14C-cotinine from 14C-nicotine

✍ Scribed by Dhimant H. Desai; Mirjana V. Djordjevic; Shantu Amin

Publisher
John Wiley and Sons
Year
1991
Tongue
French
Weight
198 KB
Volume
29
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

A convenient synthesis with analytical monitoring of ^14^C‐cotinine is reported. ^14^C‐Nicotine was converted into ^14^C‐dibromocotinine hydrobromide perbromide. Debromination, achieved by using Zn dust/acetic acid, resulted in high yields (71%) of ^14^C‐cotinine.

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