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A new pteridine synthesis

โœ Scribed by W.J. Irwin; D.G. Wibberley


Book ID
104245125
Publisher
Elsevier Science
Year
1972
Tongue
French
Weight
101 KB
Volume
13
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


A New Pteridine Synthesis
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

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## Abstract A new synthesis of pteridines possessing a (substituted) (__Z__)โ€3โ€hydroxypropโ€1โ€enyl group at C(6) is based on the acylation of 4โ€aminoโ€5โ€nitrosopyrimidines with dienoic acid chlorides, followed by a highโ€yielding intramolecular heteroโ€__Dielsโ€“Alder__ cycloaddition and cleavage of the

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## Abstract Reaction of 2โ€aminopyrazine 1 with isothiocyanate, isocyanate or dithioketal reagent furnished pteridines **3,4** in good yield. Thioxo compound **3a** was chlorinated, methylated and subsequently displaced by amines. A simple oneโ€step synthesis of heterocondensed pteridines **8โ€“13** by

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