A new pteridine synthesis
โ Scribed by W.J. Irwin; D.G. Wibberley
- Book ID
- 104245125
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- French
- Weight
- 101 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
## Abstract A new synthesis of pteridines possessing a (substituted) (__Z__)โ3โhydroxypropโ1โenyl group at C(6) is based on the acylation of 4โaminoโ5โnitrosopyrimidines with dienoic acid chlorides, followed by a highโyielding intramolecular heteroโ__DielsโAlder__ cycloaddition and cleavage of the
## Abstract Reaction of 2โaminopyrazine 1 with isothiocyanate, isocyanate or dithioketal reagent furnished pteridines **3,4** in good yield. Thioxo compound **3a** was chlorinated, methylated and subsequently displaced by amines. A simple oneโstep synthesis of heterocondensed pteridines **8โ13** by