A New Approach to the Stereospecific Synthesis of Phospholipids. The Use of l -Glyceric Acid for the Preparation of Diacylglycerols, Phosphatidylcholines, and Related Derivatives
β Scribed by Roodsari, Farzaneh S.; Wu, Dongpei; Pum, Gregory S.; Hajdu, Joseph
- Book ID
- 127044676
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 257 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A novel stereospecific synthesis of biologically active ether-phospholipids is reported. Ether phospholipids are among the most potent biologically active phospholipid derivatives.ls2 Naturally occuring as membrane-components, a number of l-sn-alkoxyglycero-phosphorylcholines have been shown to be r
A new stereospecific synthesis of lysophosphatidylcholines is reported. The sequence relies on orthogonal protection of hydroxyl groups derived from glyceric acid, using fluorenylmethylcarbonate versus tetrahydropyranyl ether functions, that allow regiospecific introduction of substituents to obtain
The Publisher regrets that the oxygen atom and the double bond of the carbonyl group of structure 5 of Scheme 1 were omitted. The correct version is printed below: Scheme 1.