A new stereospecific synthesis of lysophosphatidylcholines is reported. The sequence relies on orthogonal protection of hydroxyl groups derived from glyceric acid, using fluorenylmethylcarbonate versus tetrahydropyranyl ether functions, that allow regiospecific introduction of substituents to obtain
Erratum to “A new approach to the synthesis of lysophosphatidylcholines and related derivatives”: [Tetrahedron Lett. 44 (2003) 5875]
✍ Scribed by Niloufar Bibak; Joseph Hajdu
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 59 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The Publisher regrets that the oxygen atom and the double bond of the carbonyl group of structure 5 of Scheme 1 were omitted. The correct version is printed below: Scheme 1.
📜 SIMILAR VOLUMES
Footnote 5 of the above Tetrahedron Letter states that ''The spontaneous rearrangement of Sch. 49028 into phomactin A was observed by Pattenden et al. during their synthesis, see ref. 4. 1 '' However, it should be made absolutely clear that Goldring and Pattenden did not state in their paper 1 that
Scheme 2. Retrosynthetic analysis of reported structure 3 and biosynthetically expected isomer 4.
N-Indolylethyl-Z-pyridones bearing appropriate B-dicarbonyl in the 3iposition have been cyclised to pentacyclic indoles indolenines by catalysis with trifluoroacetic anhydride.