Stereospecific synthesis of ether and thioether phospholipids. The use of L-glyceric acid as a chiral phospholipid precursor
โ Scribed by Bhatia, Suresh K.; Hajdu, Joseph
- Book ID
- 126542433
- Publisher
- American Chemical Society
- Year
- 1988
- Tongue
- English
- Weight
- 833 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
A novel stereospecific synthesis of biologically active ether-phospholipids is reported. Ether phospholipids are among the most potent biologically active phospholipid derivatives.ls2 Naturally occuring as membrane-components, a number of l-sn-alkoxyglycero-phosphorylcholines have been shown to be r
&mm6fy : The four possible stereoisomers of a$dihydroxyaldehydes, useful building blocks for the synthesis of fatty acids metabolites, are synthesized via epoxy-tetrols derived from D-isoascorbic and L-ascorbic acids. The general method we develop allows the synthesis of chiral a-hydroxyaldehydes as