ChemInform Abstract: A New and Efficient
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A. M. BERNARD; M. T. COCCO; C. CONGIU; V. ONNIS; P. P. PIRAS
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Article
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2010
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John Wiley and Sons
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A New and Efficient Synthesis of Phthalazin-1(2H)-ones. -Treating readily available ethers (III) with catalytic acid under dry conditions provides an efficient synthesis of phthalazin-1(2H)-ones (IV). Using moist solvents results in hydrolysis [cf. (V)]. Treatment of (IIIa) with catalytic AlCl 3 lea