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ChemInform Abstract: Synthesis of 2-(2-Hydroxybenzyl)phthalazin-1(2H)-ones.

โœ Scribed by V. a. Osyanin; E. A. Ivleva; Yu. N. Klimochkin


Publisher
John Wiley and Sons
Year
2011
Weight
22 KB
Volume
42
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A New and Efficient
โœ A. M. BERNARD; M. T. COCCO; C. CONGIU; V. ONNIS; P. P. PIRAS ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 34 KB ๐Ÿ‘ 1 views

A New and Efficient Synthesis of Phthalazin-1(2H)-ones. -Treating readily available ethers (III) with catalytic acid under dry conditions provides an efficient synthesis of phthalazin-1(2H)-ones (IV). Using moist solvents results in hydrolysis [cf. (V)]. Treatment of (IIIa) with catalytic AlCl 3 lea