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A mild and efficient route to Schiff base derivatives of amino acids

โœ Scribed by O'Donnell, Martin J.; Polt, Robin L.


Book ID
115470601
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
598 KB
Volume
47
Category
Article
ISSN
0022-3263

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A new and efficient route to amino deriv
โœ Alexei Nemazany; Norbert Haider ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 265 KB

## Abstract Reaction of __N__โ€substituted amides of 2โ€chloroโ€ or 4โ€chloronicotinic acid with CHโ€acidic nitriles in the presence of a base provides a convenient access to amino derivatives of 1,6โ€naphthyridโ€5(6__H__)โ€one, compounds of type 4 and 5, or 2,7โ€naphthyridโ€1(2__H__)โ€one 7.