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A genetic perspective on coeliac disease

✍ Scribed by Gosia Trynka; Cisca Wijmenga; David A. van Heel


Book ID
116758291
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
1013 KB
Volume
16
Category
Article
ISSN
1471-4914

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πŸ“œ SIMILAR VOLUMES


Genetics in coeliac disease
✍ David A. van Heel; Karen Hunt; Luigi Greco; Cisca Wijmenga πŸ“‚ Article πŸ“… 2005 πŸ› Elsevier Science 🌐 English βš– 160 KB
Genetic epidemiology of coeliac disease
✍ J. L. Tiwari; H. Betuel; L. Gebuhrer; Dr. N. E. Morton; D. C. Rao πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 309 KB

Segregation analysis favors a gene additive on liability with a frequency of 0.022, which is nearly recessive on the penetrance scale. Less than one-eighth of DR3 and DR7 haplotypes carry a determinant for coeliac disease. There is significant excess of DR3/7 heterozygotes among patients, indicating

HLA-related genetic risk for coeliac dis
✍ M.G. Limongelli; M. Bourgey; O. Esposito; R. Troncone; M.E. Camarca; R. Di Mase; πŸ“‚ Article πŸ“… 2007 πŸ› Elsevier Science 🌐 English βš– 63 KB