Segregation analysis favors a gene additive on liability with a frequency of 0.022, which is nearly recessive on the penetrance scale. Less than one-eighth of DR3 and DR7 haplotypes carry a determinant for coeliac disease. There is significant excess of DR3/7 heterozygotes among patients, indicating
The genetic epidemiology of coeliac disease
โ Scribed by Anthony Ellis
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 159 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0741-0395
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