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A general approach to the synthesis of 14C-labeled photoactive acrylic acids

✍ Scribed by Taj Mohammad; Harry Morrison

Publisher
John Wiley and Sons
Year
1991
Tongue
French
Weight
325 KB
Volume
29
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Condensation of aromatic carboxaldehydes with [2‐^14^C]‐malonic acid under Knoevenagel conditions provides corresponding β‐aryl substituted [α‐^14^C]‐acrylic acids. The reaction is applicable to both aromatic and heteroaromatic aldehydes under controlled reaction conditions leading to moderate to good yields.

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