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A dual fluorinated and iodinated radiotracer for PET and SPECT imaging of β-amyloid plaques in the brain

✍ Scribed by Hiroyuki Watanabe; Masahiro Ono; Hiroyuki Kimura; Shinya Kagawa; Ryuichi Nishii; Takeshi Fuchigami; Mamoru Haratake; Morio Nakayama; Hideo Saji


Book ID
113496098
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
531 KB
Volume
21
Category
Article
ISSN
0960-894X

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✍ Dr. Emmanuelle Briard; Dr. David Orain; Dr. Christian Beerli; Dr. Andreas Billic 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 452 KB

## Abstract FTY720 (fingolimod, Gilenya®) is a sphingosine 1‐phosphate (S1P) receptor modulator that shows significant therapeutic efficacy after oral administration to patients of multiple sclerosis. Because FTY720 does not contain any atom whose PET or SPECT radioisotope would have a half‐life co