ChemInform Abstract: Novel Quinoxaline Derivatives for in vivo Imaging of β-Amyloid Plaques in the Brain.

✍ Scribed by Mengchao Cui; Masahiro Ono; Hiroyuki Kimura; Boli Liu; Hideo Saji

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 20 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201148181

✦ Synopsis

Abstract

In a search for new probes to detect β‐amyloid plaques in the brain of patients with Alzheimer′s disease, the radioiodinated quinoxaline derivative (I) is found to show specific labeling of Aβ plaques.