A Convenient Synthesis of Uracil 2-C 14 from Urea 1
✍ Scribed by Mandel, H. George; Brown, Curtis L.
- Book ID
- 126855668
- Publisher
- American Chemical Society
- Year
- 1952
- Tongue
- English
- Weight
- 264 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0002-7863
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## Abstract A convenient synthesis with analytical monitoring of ^14^C‐cotinine is reported. ^14^C‐Nicotine was converted into ^14^C‐dibromocotinine hydrobromide perbromide. Debromination, achieved by using Zn dust/acetic acid, resulted in high yields (71%) of ^14^C‐cotinine.
## Abstract A simple and convenient laboratory procedure is described by which hordenine (III), labelled at the carbon residing on the benzene ring, can be synthesized by decarboxylation of 3‐ [^14^C]‐tyrosine (1) and subsequent reductive methylation of the resulting tyramine (II).
## Abstract A convenient synthesis of [1‐^14^C]acetylcholine iodide in two steps is described. β‐Dimethylaminoethanol is acetylated with [1‐^14^C]acetic anhydride and the ester β‐dimethylaminoethyl [1‐^14^C]acetate quaternised with methyl iodide to afford [1‐^14^C]acetylcholine iodide in an overall
## Abstract [2,6‐^14^C]‐2‐chloroisonicotinic acid (1) was prepared by kinetically controlled lithiation and carbonation of [2,6‐^14^C]‐2,6‐dichloropyridine, followed by reduction using hydrazine and potassium hydroxide. Copyright © 2001 John Wiley & Sons, Ltd.