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A convenient synthesis of [1-14C]acetylcholine iodide

✍ Scribed by B. Anjaneyulu

Publisher
John Wiley and Sons
Year
1985
Tongue
French
Weight
190 KB
Volume
22
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

A convenient synthesis of [1‐^14^C]acetylcholine iodide in two steps is described. β‐Dimethylaminoethanol is acetylated with [1‐^14^C]acetic anhydride and the ester β‐dimethylaminoethyl [1‐^14^C]acetate quaternised with methyl iodide to afford [1‐^14^C]acetylcholine iodide in an overall material yield of 50–52% and radiochemical yield 18%.

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