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(+)-[76Br]A-69024: a non-benzazepine radioligand for studies of dopamine D1 receptors using PET

✍ Scribed by Michael Kassiou; Christian Loc’h; Michel Bottlaender; Karine Mardon; Michele Ottaviani; Christine Coulon; Andrew Katsifis; Bernard Maziere

Book ID: 117687811
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 580 KB
Volume: 29
Category: Article
ISSN: 0969-8051
DOI: 10.1016/s0969-8051(01)00306-7

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## Abstract (±)‐1‐(2‐bromo‐4,5‐dimethoxybenzyl)‐7‐hydroxy‐6‐methoxy‐2‐[^11^C]‐methyl‐1,2,3,4‐tetrahydroisoquinoline, (HCJA‐69024, a selective ligand for the D1 receptor was prepared by __N__‐alkylation of (±)__N__‐desmethyl A‐69024 with [^11^C]methyl iodide in DMF. The radiotracer was purified by s