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[11C]A-69024: A potent and selective non-benzazepine radiotracer for in vivo studies of dopamine D1 receptors

✍ Scribed by Michael Kassiou; Ursula Scheffel; Hayden T. Ravert; William B. Mathews; John L. Musachio; Richard M. Lambrecht; Robert F. Dannals

Book ID
116171980
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
787 KB
Volume
22
Category
Article
ISSN
0969-8051

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Radiosynthesis of (±)-1-(2-bromo-4,5-dim
Radiosynthesis of (±)-1-(2-bromo-4,5-dimethoxybenzyl)-7-hydroxy-6-methoxy-2-[11C]-methyI-l,2,3,4-tetrahydro-isoquinoline, [11C]A-69024: A non-benzazepine antagonist for studying dopamine D1 receptors In vivo using PET
✍ Michael Kassiou; William B. Mathews; John L. Musachio; Hayden T. Ravert; Richard 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 357 KB 👁 1 views

## Abstract (±)‐1‐(2‐bromo‐4,5‐dimethoxybenzyl)‐7‐hydroxy‐6‐methoxy‐2‐[^11^C]‐methyl‐1,2,3,4‐tetrahydroisoquinoline, (HCJA‐69024, a selective ligand for the D1 receptor was prepared by __N__‐alkylation of (±)__N__‐desmethyl A‐69024 with [^11^C]methyl iodide in DMF. The radiotracer was purified by s