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Pharmacological evaluation of (+)-2-[123I]A-69024 A radioligand for in vivo studies of dopamine D1 receptors

✍ Scribed by Michael Kassiou; Karine Mardon; Filomena Mattner; Andrew Katsifis; Branko Dikic

Book ID: 117173020
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 209 KB
Volume: 69
Category: Article
ISSN: 0024-3205
DOI: 10.1016/s0024-3205(01)01156-0

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## Abstract (__S__)‐(−)‐__N__‐[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐5‐[^123^I]iodo‐2,3‐dimethoxybenzamide (TDP 517) (proposed generic name, [^123^I]epidepride) is the iodine‐123 substituted analogue of isoremoxipride (FLB 457), both of which are very potent dopamine D‐2 antagonists (epidepride K~D~ 0.02