𝔖 Bobbio Scriptorium
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50Years of poly(ADP-ribosyl)ation

✍ Scribed by Virág, László


Book ID
121322024
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
340 KB
Volume
34
Category
Article
ISSN
0098-2997

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One of the immediate eukaryotic cellular responses to DNA breakage is the covalent post-translational modification of nuclear proteins with poly(ADP-ribose) from NAD+ as precursor, mostly catalysed by poly(ADP-ribose) polymerase-1 (PARP-1). Recently several other polypeptides have been shown to cata