Role of poly(ADP-ribosyl)ation during human spermatogenesis
β Scribed by Batia Bar-Shira Maymon; Malka Cohen-Armon; Haim Yavetz; Leah Yogev; Beatriz Lifschitz-Mercer; Sandra E. Kleiman; Amnon Botchan; Ron Hauser; Gedalia Paz
- Book ID
- 116468962
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 548 KB
- Volume
- 86
- Category
- Article
- ISSN
- 1556-5653
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π SIMILAR VOLUMES
One of the immediate eukaryotic cellular responses to DNA breakage is the covalent post-translational modification of nuclear proteins with poly(ADP-ribose) from NAD+ as precursor, mostly catalysed by poly(ADP-ribose) polymerase-1 (PARP-1). Recently several other polypeptides have been shown to cata
Poly(ADP-ribose) polymerase activity was determined at various times during the in vitro life span of two human diploid fibroblast-like cell lines of different donor ages. The cell lines differed in their ability to transfer ADP-ribose, with cells from an embryonic donor exhibiting 2 to 3 times the