Poly(ADP-ribosyl)ation during chromatin remodeling steps in rat spermiogenesis
✍ Scribed by Mirella L. Meyer-Ficca; Harry Scherthan; Alexander Bürkle; Ralph G. Meyer
- Book ID
- 106089940
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 396 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0009-5915
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Poly(ADP-ribose) polymerase activity was determined at various times during the in vitro life span of two human diploid fibroblast-like cell lines of different donor ages. The cell lines differed in their ability to transfer ADP-ribose, with cells from an embryonic donor exhibiting 2 to 3 times the
Rat testis H1 proteins were poly(ADP-ribosyl)ated in vitro. The modifying product, poly(ADP-ribose), was found covalently bound to each histone variant at various extents and exhibited distinct structural features (linear and short, rather than branched and long chains). Interest was focused on the