Synthesis of 4,8‐Dimethoxy‐1,5‐naphthalenediol and Its Oxidation to 4,8‐Dimethoxy‐1,5‐naphthoquinone Formation of the new 1,5‐naphthoquinone 3 was achieved by methylation of 1,4,5,8‐naphthalenetetrol (1a) and oxidation of the dimethyl ether 1c obtained thereof. In the presence of water, 3 yields th
4,8-Dimethoxy-1,5-naphthyridine
✍ Scribed by Harlow, R. L. ;Simonsen, S. H.
- Book ID
- 114524422
- Publisher
- International Union of Crystallography
- Year
- 1977
- Weight
- 248 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0567-7408
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## Abstract Ethyl 1‐ethyl‐7‐methyl‐4‐oxo‐1,4‐dihydro[1,8]naphthyridine‐3‐carboxylate (**1**), precursor of nalidixic acid, has been converted in two steps through ([1,8]naphthyridin‐3‐yl)carbonylguanidine derivatives into substituted pyrimido[4,5‐__b__] and [5,4‐__c__][1,8]naphthyridines.