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Naphthyridines. Part IV. Preparation of anthyridines and pyrimido-[4,5-b][1,8]naphthyridines from 2-amino-1,8-naphthyridines

✍ Scribed by Harper, J. F.; Wibberley, D. G.


Book ID
118736507
Publisher
The Royal Society of Chemistry
Year
1971
Tongue
English
Weight
622 KB
Category
Article
ISSN
0022-4952

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Synthesis of substituted pyrimido[4,5-b]
✍ Christophe Plisson; Jacques Chenault πŸ“‚ Article πŸ“… 2001 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 56 KB

## Abstract Ethyl 1‐ethyl‐7‐methyl‐4‐oxo‐1,4‐dihydro[1,8]naphthyridine‐3‐carboxylate (**1**), precursor of nalidixic acid, has been converted in two steps through ([1,8]naphthyridin‐3‐yl)carbonylguanidine derivatives into substituted pyrimido[4,5‐__b__] and [5,4‐__c__][1,8]naphthyridines.

ChemInform Abstract: 1,8-Naphthyridines.