Using the dominant lethal assay, the ability of fosfestrol, a diethylstilboestrol derivate, to induce mutations in male mice was tested and confirmed. Up to 300 mg/kg of fosfestrol the induction of mutations occurs exclusively in spermatozoa. A dose of 600 mg/kg of fosfestrol induces dominant lethal
✦ LIBER ✦
467 Induction of dominant lethal mutations in male mice by perezone
✍ Scribed by G. Chamorro; L. Garduño-Siliciano; M. Salazar
- Book ID
- 119538236
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 58 KB
- Volume
- 144
- Category
- Article
- ISSN
- 0378-4274
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