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[3H]BMS-599240 — A novel tritiated ligand for the characterization of BACE1 inhibitors

✍ Scribed by Lawrence G. Iben; Lisa Kopcho; Jovita Marcinkeviciene; Changsheng Zheng; Lorin A. Thompson; Charles F. Albright; Jeremy H. Toyn

Book ID
113587774
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
324 KB
Volume
593
Category
Article
ISSN
0014-2999

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A tritiated photoaffinity ligand for the dopamine reuptake transporter protein, 1-[2-(diphenylmethoxy) ethyl] -4-[ 3-(3 -azidophenyl)-2,3-ditritiopropyl]piperazine, of specific activity 41.8 Cilmmol, was prepared in six steps starting from 1-[2-(diphenylmethoxy)ethyl] piperazine.