✦ LIBER ✦

Solubilization and characterization of binding sites for [3H]NE-100, a novel and potent sigma1 ligand, from guinea pig brain

✍ Scribed by Shigeyuki Chakil; Shigeru Okuyama; Shinichi Ogawa; Makoto Tanaka; Makoto Muramatsu; Atsuro Nakazato; Kazuyuki Tomisawa

Book ID: 116019302
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 661 KB
Volume: 59
Category: Article
ISSN: 0024-3205
DOI: 10.1016/0024-3205(96)00458-4

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Characteristics of binding of [3H]NE-100

Characteristics of binding of [3H]NE-100, a novel sigma-receptor ligand, to guinea-pig brain membranes

✍ M. Tanaka; T. Shirasaki; S. Kaku; M. Muramatsu; S. Otomo 📂 Article 📅 1995 🏛 Springer-Verlag 🌐 English ⚖ 868 KB

RTI-4793-14, a new ligand with high affi

RTI-4793-14, a new ligand with high affinity and selectivity for the (+)-MK801-insensitive [3H]1-[1-(2 thienyl)cyclohexyl]piperidine binding site (PCP site 2) of guinea pig brain

✍ Carl B. Goodman; D. Nigel Thomas; Agu Pert; Betsey Emilien; Jean L. Cadet; F. Iv 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 771 KB

## Abstract [^3^H]TCP, an analog of the dissociative anesthetic phencyclidine (PCP), binds with high affinity to two sites in guinea pig brain membranes, one that is MK‐801 sensitive and one that is not. The MK‐801‐sensitive site (PCP site 1) is associated with NMDA receptors, whereas the MK‐801‐in