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Synthesis of tritiated 1-[2-(diphenylmethoxy)ethyl]-4-[3-(3-azidophenyl)propyl]piperazine ([3H]-meta azido GBR-12935), a photoaffinity ligand for the dopamine reuptake site

✍ Scribed by A. Thurkauf; B. de Costa; P. Berger; S. Paul; K. C. Rice

Publisher: John Wiley and Sons
Year: 1991
Tongue: French
Weight: 201 KB
Volume: 29
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580290202

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✦ Synopsis

A tritiated photoaffinity ligand for the dopamine reuptake transporter protein, 1-[2-(diphenylmethoxy) ethyl] -4-[ 3-(3 -azidophenyl)-2,3-ditritiopropyl]piperazine, of specific activity 41.8 Cilmmol, was prepared in six steps starting from 1-[2-(diphenylmethoxy)ethyl] piperazine.

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