39-174 - Association between presenilin-1 (S182) gene polymorphism and Alzheimer's disease in the Spanish population
โ Scribed by K. Beyer; J.I. Lao; M.A. Sellers; X.A. Alvarez; R. Cacabelos
- Book ID
- 118511861
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 678 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0006-3223
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๐ SIMILAR VOLUMES
## Wragg et al. [1996: Lancet 347:509-512] recorded an association between the intronbased presenilin 1 (PS1) genotype 1/1 and late-onset Alzheimer's disease (AD). This study was performed to determine if there is a similar association in the Chinese population. Ninety-one AD cases, 50 multiinfarc
Mutations in the Presenilin 1 (PS1) gene on chromosome 14 cause most early-onset familial Alzheimer's disease (AD). An intronic polymorphism in the PS1 gene was recently identified and reported to be associated with late-onset AD [Wragg et al., Lancet 347: 509-512, 1996]. The authors found an excess