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Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease

โœ Scribed by M Wragg; C Talbot; M Hutton; Alison Goate


Book ID
118561603
Publisher
The Lancet
Year
1996
Tongue
English
Weight
528 KB
Volume
347
Category
Article
ISSN
0140-6736

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No association or linkage between an int
โœ W.K. Scott; L.H. Yamaoka; P.A. Locke; B.L. Rosi; P.C. Gaskell; A.M. Saunders; P. ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 34 KB ๐Ÿ‘ 2 views

Recent reports have shown an association between an intronic polymorphism of the presenilin-1 (PSEN1) gene and late-onset (age at onset > 65) familial and sporadic (no family history) Alzheimer disease (AD). The reported association was independent of the effect of the only previously identified gen