## Abstract We explored the potential effect of catechol‐__O__‐methyltransferase (COMT) genetic polymorphism on the pharmacokinetics and pharmacodynamics of a standard oral dose of levodopa in patients with Parkinson's disease (PD). We prospectively collected blood samples for COMT genotyping from
✦ LIBER ✦
3.053 ASSOCIATION OF CATECHOL-O-METHYLTRANSFERASE POLYMORPHISMS WITH PARKINSON'S DISEASE AND MOTOR COMPLICATIONS
✍ Scribed by B. Yin; L. Zhang; W. Sun; W. Wang
- Book ID
- 117755156
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 60 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1353-8020
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Genetic polymorphism of catechol-O-methy
✍
Manuela Contin; Paolo Martinelli; Mirella Mochi; Roberto Riva; Fiorenzo Albani;
📂
Article
📅
2005
🏛
John Wiley and Sons
🌐
English
⚖ 195 KB
High and low activity alleles of catecho
✍
Hiroshi Kunugi; Shinichiro Nanko; Akira Ueki; Emiko Otsuka; Mineko Hattori; Farz
📂
Article
📅
1997
🏛
Elsevier Science
🌐
English
⚖ 54 KB
Effects of tolcapone, a catechol-O-methy
✍
M. Yamamoto; M. Yokochi; S. Kuno; Y. Hattori; Y. Tsukamoto; H. Narabayashi; H. T
📂
Article
📅
1997
🏛
Springer
🌐
English
⚖ 517 KB
Genotypes of catechol-O-methyltransferas
✍
Myung Sik Lee; Chul Hyoung Lyoo; Ismo Ulmanen; Ann-Christine Syvänen; Juha O Rin
📂
Article
📅
2001
🏛
Elsevier Science
🌐
English
⚖ 85 KB
Catechol-O-methyltransferase Val158Met a
✍
Lonneke M.L. de Lau; Dagmar Verbaan; Johan Marinus; Peter Heutink; Jacobus J. va
📂
Article
📅
2011
🏛
John Wiley and Sons
🌐
English
⚖ 1006 KB
## Abstract ## Background: The A‐allele of the catechol‐__O__‐methyltransferase (__COMT__) Val158Met polymorphism is associated with decreased enzymatic activity and higher dopamine availability. ## Methods: We studied 219 patients with PD who were free of dyskinesias at baseline and underwent t
The effect of monoamine oxidase B (MAOB)
✍
M. Białecka; M. Droździk; G. Kłodowska-Duda; K. Honczarenko; B. Gawrońska-Szklar
📂
Article
📅
2004
🏛
John Wiley and Sons
🌐
English
⚖ 121 KB