✦ LIBER ✦

2,3,4,4a,5,6,7,7a-Octahydro-1H-benzofuro[3,2-e]isoquinoline: a new morphine fragment

✍ Scribed by Ciganek, Engelbert

Book ID: 121487475
Publisher: American Chemical Society
Year: 1981
Tongue: English
Weight: 266 KB
Volume: 103
Category: Article
ISSN: 0002-7863
DOI: 10.1021/ja00410a065

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and Opioid Activity of Enantio

Synthesis and Opioid Activity of Enantiomeric N -Substituted 2,3,4,4a,5,6,7,7a-Octahydro-1 H -benzofuro[3,2- e ]isoquinolines

✍ Hsin, Ling-Wei; Chang, Li-Te; Rothman, Richard B.; Dersch, Christina M.; Fishbac 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 849 KB

Synthesis and Opioid Activity of 7-Oxyge

Synthesis and Opioid Activity of 7-Oxygenated 2,3,4,4a,5,6,7,7a-octahydro-1H-benzofuro[3,2-e]isoquinolinols

✍ Cheng, Chen-Yu; Hsin, Ling-Wei; Tsai, Ming-Cheng; Schmidt, William K.; Smith, Ch 📂 Article 📅 1994 🏛 American Chemical Society 🌐 English ⚖ 922 KB

Synthesis of 3-methyl-2,3,4,4a,5,6-hexah

Synthesis of 3-methyl-2,3,4,4a,5,6-hexahydro-1H-benzofuro[3,2-e]isoquinoline-7(7aH)-ones

✍ Dwight D. Weller; Doreen L. Weller 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 219 KB

The 2,3,4,4a,5, isoquinoline-7(7aH)-one ring system is prepared from a 4-arylpyridine precursor by sequential intramolecular enolate addition to a pyridinium ion, Dieckmann cyclization, and catalytic hydrogenation.

Novel radical synthesis of morphine frag

Novel radical synthesis of morphine fragments spiro[benzofuran-3(2H),4′-piperidine] and octahydro-1H-benzofuro[3,2-e]isoquinoline

✍ Chen-Yu Cheng; Ling-Wei Hsin; Jing-Ping Liou 📂 Article 📅 1996 🏛 Elsevier Science 🌐 French ⚖ 569 KB

Synthesis of morphine fragments spiro[be

Synthesis of morphine fragments spiro[benzofuran-3(2H),4′-piperidine] and octahydro-1H-benzofuro[3,2-e]isoquinoline by intramolecular Heck reaction

✍ Chen-Yu Cheng; Jing-Ping Liou; Mei-Jing Lee 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 209 KB

As a better alternative to radical cyclization, 5-(2-bromo-6-methoxyphenoxy)-2-methyl-l,2,3,4,5,6,7,8-octahydroisoquinoline (2) and its 1-oxo analog 3 underwent Pdcatalyzed intramolecular cyclization to give the tetracyclic (ACNO) morphine fragments 5 and 6 respectively. 4-[(2'-Iodo-6'-methoxyphenox

ChemInform Abstract: Novel Radical Synth

ChemInform Abstract: Novel Radical Synthesis of Morphine Fragments Spiro(benzofuran-3(2H),4′ -piperidine) and Octahydro-1H-benzofuro(3,2-e)isoquinoline.

✍ C.-Y. CHENG; L.-W. HSIN; J.-P. LIOU 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB