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19-Nor-10-azasteroids: A Novel Class of Inhibitors for Human Steroid 5α-Reductases 1 and 2

✍ Scribed by Guarna, Antonio; Belle, Catherine; Machetti, Fabrizio; Occhiato, Ernesto G.; Payne, Andrew H.; Cassiani, Chiara; Comerci, Alessandra; Danza, Giovanna; De Bellis, Alessandra; Dini, Stefania; Marrucci, Alessandro; Serio, Mario


Book ID
125530744
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
745 KB
Volume
40
Category
Article
ISSN
0022-2623

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A Concise Route to 19-Nor-10-azasteroids, a New Class of Steroid 5α-Reductase Inhibitors. Part 3. Synthesis of (+)-19-Nor-10azatestosterone and (+)-17β-(Acetyloxy)-(5β)-10-azaestr-1-en-3-one. -The title compounds are of interest, since 5α-reductase inhibitors (by reducing the level of dihydrotesto