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A Concise Route to 19-Nor-10-azasteroids, a New Class of Steroid 5α-Reductase Inhibitors. 3. 1 Synthesis of (+)-19-Nor-10-azatestosterone and (+)-17β-(Acetyloxy)-(5β)-10-azaestr-1-en-3-one

✍ Scribed by Guarna, Antonio; Occhiato, Ernesto G.; Machetti, Fabrizio; Scarpi, Dina

Book ID
126258555
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
113 KB
Volume
63
Category
Article
ISSN
0022-3263

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ChemInform Abstract: A Concise Route to 19-Nor-10-azasteroids, a New Class of Steroid 5α-Reductase Inhibitors. Part 3. Synthesis of (+)-19-Nor-10-azatestosterone and (+)-17β-(Acetyloxy)-(5β)-10-azaestr-1-en-3-one.
✍ A. GUARNA; E. G. OCCHIATO; F. MACHETTI; D. SCARPI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 43 KB 👁 2 views

A Concise Route to 19-Nor-10-azasteroids, a New Class of Steroid 5α-Reductase Inhibitors. Part 3. Synthesis of (+)-19-Nor-10azatestosterone and (+)-17β-(Acetyloxy)-(5β)-10-azaestr-1-en-3-one. -The title compounds are of interest, since 5α-reductase inhibitors (by reducing the level of dihydrotesto