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ChemInform Abstract: 19-Nor-10-azasteroids, a New Class of Steroid 5α-Reductase Inhibitors. Part 2. X-Ray Structure, Molecular Modeling, Conformational Analysis of 19-Nor-10-azasteroids and Comparison with 4-Azasteroids and 6-Azasteroids.

✍ Scribed by A. GUARNA; E. G. OCCHIATO; F. MACHETTI; A. MARRUCCI; G. DANZA; M. SERIO; P. PAOLI


Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
29
Category
Article
ISSN
0931-7597

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✍ A. GUARNA; E. G. OCCHIATO; F. MACHETTI; D. SCARPI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 43 KB 👁 1 views

A Concise Route to 19-Nor-10-azasteroids, a New Class of Steroid 5α-Reductase Inhibitors. Part 3. Synthesis of (+)-19-Nor-10azatestosterone and (+)-17β-(Acetyloxy)-(5β)-10-azaestr-1-en-3-one. -The title compounds are of interest, since 5α-reductase inhibitors (by reducing the level of dihydrotesto