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ChemInform Abstract: 19-Nor-10-azasteroids: A Novel Class of Inhibitors for Human Steroid 5. alpha.-Reductases 1 and 2.

โœ Scribed by A. GUARNA; C. BELLE; F. MACHETTI; E. G. OCCHIATO; A. H. PAYNE; C. CASSIANI; A. COMERCI; G. DANZA; A. DE BELLIS; S. DINI; A. MARRUCCI; M. SERIO

Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
28
Category
Article
ISSN
0931-7597

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โœ A. GUARNA; E. G. OCCHIATO; F. MACHETTI; D. SCARPI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 43 KB ๐Ÿ‘ 1 views

A Concise Route to 19-Nor-10-azasteroids, a New Class of Steroid 5ฮฑ-Reductase Inhibitors. Part 3. Synthesis of (+)-19-Nor-10azatestosterone and (+)-17ฮฒ-(Acetyloxy)-(5ฮฒ)-10-azaestr-1-en-3-one. -The title compounds are of interest, since 5ฮฑ-reductase inhibitors (by reducing the level of dihydrotesto