13C Scrambling of [5-13C]5-cyclodecynone
โ Scribed by Michael F Wempe; John R Grunwell *
- Book ID
- 104210749
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 155 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
Scrambling of [5-13 C]5-cyclodecynone occurs as a result of acidic conditions that preclude its rapid consumption.
๐ SIMILAR VOLUMES
## Abstract 5โ[4,5โ^13^C~2~]โ and 5โ[1,5โ^13^C~2~]Aminolevulinic acid (ALA) have been synthesized by the Gabriel condensation of potassium phthalimide with ethyl bromo[1,2โ^13^C~2~]acetate (derived from [1,2โ^13^C~2~]acetic acid) or ethyl bromo[2โ^13^C]โacetate (derived from sodium [2โ^13^C]acetate
## Abstract The condensation of ethyl acetoacetateโ^13^C~4~ and ethyl bromoacetateโ^13^C~2~ afforded, in seven steps, (1,2,3,4,5โ^13^C~5~) 5โ(diethylphosphono)โ2โpentanone ethylene ketal 9. The reaction of this labelled compound with 7โ[[(1,1โdimethylethyl)โdimethylsilyl]oxy]โ1,6,6a,7,8,9,9a, 9bโoc
The preparation of t3C-labeled ribonucleosides starting from D-[t3C~]glucose in 45% overall yield is described. The key of this short synthetic way is the dehomologation of di-O-isopropylidene hexofuranose 2 with periodic acid and NaBI-I4 that afforded stereoselectively the labeled ribofuranose deri