𝔖 Bobbio Scriptorium
✦   LIBER   ✦

β-Trimethylsilylethanesulfonyl chloride (SES-Cl): A new reagent for protection of amines

✍ Scribed by Steven M Weinreb; Donald M Demko; Thomas A Lessen; James P Demers

Book ID
104218540
Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
181 KB
Volume
27
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

The title compound, easily prepared in two steps from vinyltrimethylsilane, is a useful reagent for the protection of primary and secondary amines as their sulfonamides, which are cleaved by fluoride ion.

Sulfonamides are among the most stable of amine protecting groups.' However,

📜 SIMILAR VOLUMES

A new reagent for solid and solution pha
A new reagent for solid and solution phase synthesis of protected guanidines from amines
✍ Yaw Fui Yong; Jennifer A. Kowalski; Jason C. Thoen; Mark A. Lipton 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 217 KB

A new reagent --4-nitro-l-H-pyrazole-l-[N, N'-bis(ten-butoxycarbonyl)]cmboxamidine --has been develolxd to effect the rapid a~l efficient synthesis of I~(~)-pmtected guanidin~ from and secendm3, amines. The reagent is a more eleclrophilic, sad comfy more derivative of the literature reagent l-H-pyra