Chemoenzymatic dynamic kinetic resolution of b-hydroxy nitriles 1 has been carried out using Candida antarctica lipase B and a ruthenium catalyst. The use of a hydrogen source to depress ketone formation in the dynamic kinetic resolution yields the corresponding acetates 2 in good yield and high ena
✦ LIBER ✦
β-Aminopeptidase-Catalyzed Biotransformations of β2-Dipeptides: Kinetic Resolution and Enzymatic Coupling
✍ Scribed by Tobias Heck; Artur Reimer; Dieter Seebach; James Gardiner; Gildas Deniau; Aneta Lukaszuk; Hans-Peter E. Kohler; Birgit Geueke
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 334 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1439-4227
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